Human Cytomegalovirus Stimulates Cellular IKK2 Activity and Requires the Enzyme for Productive Replication

Human cytomegalovirus (HCMV) exploits the host transcription factor NF-κB to enhance its own replication, dissemination, and reactivation from latency. Here we report that HCMV infection activates the upstream IκB kinase (IKK) complex and that its catalytic IKK2 subunit is required for HCMV-induced...

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Detalhes bibliográficos
Main Authors: Caposio, Patrizia, Dreano, Michel, Garotta, Gianni, Gribaudo, Giorgio, Landolfo, Santo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC353729/
https://ncbi.nlm.nih.gov/pubmed/14990741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.6.3190-3195.2004
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