Phosphorothioate-Modified Oligodeoxynucleotides Inhibit Human Cytomegalovirus Replication by Blocking Virus Entry

Studies in animal models have provided evidence that Toll-like receptor 9 (TLR9) agonists, such as synthetic oligodeoxynucleotides (ODNs) that contain immunostimulatory deoxycytidyl-deoxyguanosine (CpG) motifs (CpG ODNs), protect against a wide range of viral pathogens. This antiviral activity has b...

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Bibliografiska uppgifter
Huvudupphovsmän: Luganini, Anna, Caposio, Patrizia, Landolfo, Santo, Gribaudo, Giorgio
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2008
Ämnen:
Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258505/
https://ncbi.nlm.nih.gov/pubmed/18180342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00987-07
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