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Reducing the dimensionality of the protein-folding search problem

How does a folding protein negotiate a vast, featureless conformational landscape and adopt its native structure in biological real time? Motivated by this search problem, we developed a novel algorithm to compare protein structures. Procedures to identify structural analogs are typically conducted...

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Библиографические подробности
Главные авторы: Chellapa, George D, Rose, George D
Формат: Artigo
Язык:Inglês
Опубликовано: Wiley Subscription Services, Inc., A Wiley Company 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537243/
https://ncbi.nlm.nih.gov/pubmed/22692765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2106
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