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A theoretical search for folding/unfolding nuclei in three-dimensional protein structures
When a protein folds or unfolds, it has to pass through many half-folded microstates. Only a few of them can be seen experimentally. In a two-state transition proceeding with no accumulation of metastable intermediates [Fersht, A. R. (1995) Curr. Opin. Struct. Biol. 5, 79–84], only the semifolded mi...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
1999
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC18028/ https://ncbi.nlm.nih.gov/pubmed/10500171 |
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