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A theoretical search for folding/unfolding nuclei in three-dimensional protein structures

When a protein folds or unfolds, it has to pass through many half-folded microstates. Only a few of them can be seen experimentally. In a two-state transition proceeding with no accumulation of metastable intermediates [Fersht, A. R. (1995) Curr. Opin. Struct. Biol. 5, 79–84], only the semifolded mi...

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Bibliografiske detaljer
Main Authors: Galzitskaya, Oxana V., Finkelstein, Alexei V.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC18028/
https://ncbi.nlm.nih.gov/pubmed/10500171
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