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microRNA-independent recruitment of Argonaute 1 to nanos mRNA through the Smaug RNA-binding protein

Argonaute (Ago) proteins are typically recruited to target messenger RNAs via an associated small RNA such as a microRNA (miRNA). Here, we describe a new mechanism of Ago recruitment through the Drosophila Smaug RNA-binding protein. We show that Smaug interacts with the Ago1 protein, and that Ago1 i...

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Bibliographic Details
Main Authors: Pinder, Benjamin D, Smibert, Craig A
Format: Artigo
Language:Inglês
Published: European Molecular Biology Organization 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537145/
https://ncbi.nlm.nih.gov/pubmed/23184089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.192
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