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Src controls tumorigenesis via JNK-dependent regulation of the Hippo pathway in Drosophila

Cell–cell interactions within the tumour microenvironment have crucial roles in epithelial tumorigenesis. Using Drosophila genetics, we show that the oncoprotein Src controls tumour microenvironment by Jun N-terminal kinase (JNK)-dependent regulation of the Hippo pathway. Clones of cells with elevat...

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Autors principals: Enomoto, Masato, Igaki, Tatsushi
Format: Artigo
Idioma:Inglês
Publicat: European Molecular Biology Organization 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537139/
https://ncbi.nlm.nih.gov/pubmed/23196366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.185
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