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Assembly of Subtype 1 Influenza Neuraminidase Is Driven by Both the Transmembrane and Head Domains
Neuraminidase (NA) is one of the two major influenza surface antigens and the main influenza drug target. Although NA has been well characterized and thought to function as a tetramer, the role of the transmembrane domain (TMD) in promoting proper NA assembly has not been systematically studied. Her...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537063/ https://ncbi.nlm.nih.gov/pubmed/23150659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.424150 |
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