Foxo3a transcription factor is a negative regulator of Skp2 and Skp2 SCF complex

Skp2 SCF complex displays E3 ligase activity and oncogenic activity by regulating protein ubiquitination and degradation, in turn regulating cell cycle entry, senescence and tumorigenesis. The maintenance of the integrity of Skp2 SCF complex is critical for its E3 ligase activity. The Skp2 F-box pro...

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Detaylı Bibliyografya
Asıl Yazarlar: Wu, Juan, Lee, Szu-Wei, Zhang, Xian, Han, Fei, Kwan, Suet-Yan, Yuan, Xiandao, Yang, Wei-Lei, Jeong, Yung Seong, Rezaeian, Abdol Hossein, Gao, Yuan, Zeng, Yi-Xin, Lin, Hui-Kuan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536937/
https://ncbi.nlm.nih.gov/pubmed/22310285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.26
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