Popular Computational Methods to Assess Multiprotein Complexes Derived From Label-Free Affinity Purification and Mass Spectrometry (AP-MS) Experiments

Advances in sensitivity, resolution, mass accuracy, and throughput have considerably increased the number of protein identifications made via mass spectrometry. Despite these advances, state-of-the-art experimental methods for the study of protein-protein interactions yield more candidate interactio...

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Bibliographic Details
Main Authors: Armean, Irina M., Lilley, Kathryn S., Trotter, Matthew W. B.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2013
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536891/
https://ncbi.nlm.nih.gov/pubmed/23071097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.R112.019554
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