Synthesis, Antitubercular Activity and Mechanism of Resistance of Highly Effective Thiacetazone Analogues

Defining the pharmacological target(s) of currently used drugs and developing new analogues with greater potency are both important aspects of the search for agents that are effective against drug-sensitive and drug-resistant Mycobacterium tuberculosis. Thiacetazone (TAC) is an anti-tubercular drug...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Coxon, Geoffrey D., Craig, Derek, Corrales, Rosa Milagros, Vialla, Emilie, Gannoun-Zaki, Laila, Kremer, Laurent
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2013
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536773/
https://ncbi.nlm.nih.gov/pubmed/23301038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053162
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