Downregulation of TRAF2 Mediates NIK-Induced Pancreatic Cancer Cell Proliferation and Tumorigenicity

BACKGROUND: Increased levels of NF-κB are hallmarks of pancreatic ductal adenocarcinoma (PDAC) and both classical and alternative NF-κB activation pathways have been implicated. METHODOLOGY/PRINCIPAL FINDINGS: Here we show that activation of the alternative pathway is a source for the high basal NF-...

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Detaylı Bibliyografya
Asıl Yazarlar: Döppler, Heike, Liou, Geou-Yarh, Storz, Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536768/
https://ncbi.nlm.nih.gov/pubmed/23301098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053676
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