Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ

A definitive consequence of the aging process is the progressive deterioration of higher cognitive functions. Defects in DNA repair mechanisms mostly result in accelerated aging and reduced brain function. DNA polymerase µ is a novel accessory partner for the non-homologous end-joining DNA repair pa...

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Detalhes bibliográficos
Main Authors: Lucas, Daniel, Delgado-García, José M., Escudero, Beatriz, Albo, Carmen, Aza, Ana, Acín-Pérez, Rebeca, Torres, Yaima, Moreno, Paz, Enríquez, José Antonio, Samper, Enrique, Blanco, Luis, Fairén, Alfonso, Bernad, Antonio, Gruart, Agnès
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536760/
https://ncbi.nlm.nih.gov/pubmed/23301049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053243
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