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DNA polymerase mu (Pol μ), homologous to TdT, could act as a DNA mutator in eukaryotic cells
A novel DNA polymerase has been identified in human cells. Human DNA polymerase mu (Pol μ), consisting of 494 amino acids, has 41% identity to terminal deoxynucleotidyltransferase (TdT). Human Pol μ, overproduced in Escherichia coli in a soluble form and purified to homogeneity, displays intrinsic t...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC310241/ https://ncbi.nlm.nih.gov/pubmed/10747040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.7.1731 |
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