Single-Cell and Population NF-κB Dynamic Responses Depend on Lipopolysaccharide Preparation

BACKGROUND: Lipopolysaccharide (LPS), found in the outer membrane of gram-negative bacteria, elicits a strong response from the transcription factor family Nuclear factor (NF)-κB via Toll-like receptor (TLR) 4. The cellular response to lipopolysaccharide varies depending on the source and preparatio...

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Détails bibliographiques
Auteurs principaux: Gutschow, Miriam V., Hughey, Jacob J., Ruggero, Nicholas A., Bajar, Bryce T., Valle, Sean D., Covert, Markus W.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536753/
https://ncbi.nlm.nih.gov/pubmed/23301045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0053222
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