Combinatorial processing of bacterial and host-derived innate immune stimuli at the single-cell level

During the course of a bacterial infection, cells are exposed simultaneously to a range of bacterial and host factors, which converge on the central transcription factor nuclear factor (NF)-κB. How do single cells integrate and process these converging stimuli? Here we tackle the question of how cel...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Gutschow, Miriam V., Mason, John C., Lane, Keara M., Maayan, Inbal, Hughey, Jacob J., Bajar, Bryce T., Amatya, Debha N., Valle, Sean D., Covert, Markus W.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589564/
https://ncbi.nlm.nih.gov/pubmed/30462580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-07-0423
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