Ca(V)1.2 I-II linker structure and Timothy syndrome

Ca(V) channels are multi-subunit protein complexes that enable inward cellular Ca(2+) currents in response to membrane depolarization. We recently described structure-function studies of the intracellular α1 subunit domain I-II linker, directly downstream of domain IS6. The results show the extent o...

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Bibliographic Details
Main Authors: Almagor, Lior, Chomsky-Hecht, Orna, Ben-Mocha, Adva, Hendin-Barak, Doran, Dascal, Nathan, Hirsch, Joel A.
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536733/
https://ncbi.nlm.nih.gov/pubmed/22990809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.22078
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