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Activated protein C ameliorates Bacillus anthracis lethal toxin-induced lethal pathogenesis in rats
BACKGROUND: Lethal toxin (LT) is a major virulence factor of Bacillus anthracis. Sprague Dawley rats manifest pronounced lung edema and shock after LT treatments, resulting in high mortality. The heart failure that is induced by LT has been suggested to be a principal mechanism of lung edema and mor...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536616/ https://ncbi.nlm.nih.gov/pubmed/23170801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-98 |
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