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Ablation of cardiac myosin–binding protein-C accelerates contractile kinetics in engineered cardiac tissue
Hypertrophic cardiomyopathy (HCM) caused by mutations in cardiac myosin–binding protein-C (cMyBP-C) is a heterogenous disease in which the phenotypic presentation is influenced by genetic, environmental, and developmental factors. Though mouse models have been used extensively to study the contracti...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536521/ https://ncbi.nlm.nih.gov/pubmed/23277475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210837 |
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