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Increased intracellular magnesium attenuates β-adrenergic stimulation of the cardiac Ca(V)1.2 channel
Increases in intracellular Mg(2+) (Mg(2+)(i)), as observed in transient cardiac ischemia, decrease L-type Ca(2+) current of mammalian ventricular myocytes (VMs). However, cardiac ischemia is associated with an increase in sympathetic tone, which could stimulate L-type Ca(2+) current. Therefore, the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536518/ https://ncbi.nlm.nih.gov/pubmed/23250865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210864 |
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