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Recombinant Parainfluenza Virus 5 Vaccine Encoding the Influenza Virus Hemagglutinin Protects against H5N1 Highly Pathogenic Avian Influenza Virus Infection following Intranasal or Intramuscular Vaccination of BALB/c Mice

New approaches for vaccination to prevent influenza virus infection are needed. Emerging viruses, such as the H5N1 highly pathogenic avian influenza (HPAI) virus, pose not only pandemic threats but also challenges in vaccine development and production. Parainfluenza virus 5 (PIV5) is an appealing ve...

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Bibliografiske detaljer
Main Authors: Mooney, Alaina J., Li, Zhuo, Gabbard, Jon D., He, Biao, Tompkins, S. Mark
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536407/
https://ncbi.nlm.nih.gov/pubmed/23077318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02330-12
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