Recombinant Parainfluenza Virus 5 Expressing Hemagglutinin of Influenza A Virus H5N1 Protected Mice against Lethal Highly Pathogenic Avian Influenza Virus H5N1 Challenge

A safe and effective vaccine is the best way to prevent large-scale highly pathogenic avian influenza virus (HPAI) H5N1 outbreaks in the human population. The current FDA-approved H5N1 vaccine has serious limitations. A more efficacious H5N1 vaccine is urgently needed. Parainfluenza virus 5 (PIV5),...

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Hlavní autoři: Li, Zhuo, Mooney, Alaina J., Gabbard, Jon D., Gao, Xiudan, Xu, Pei, Place, Ryan J., Hogan, Robert J., Tompkins, S. Mark, He, Biao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536412/
https://ncbi.nlm.nih.gov/pubmed/23077314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02321-12
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