Recombinant Parainfluenza Virus 5 Vaccine Encoding the Influenza Virus Hemagglutinin Protects against H5N1 Highly Pathogenic Avian Influenza Virus Infection following Intranasal or Intramuscular Vaccination of BALB/c Mice

New approaches for vaccination to prevent influenza virus infection are needed. Emerging viruses, such as the H5N1 highly pathogenic avian influenza (HPAI) virus, pose not only pandemic threats but also challenges in vaccine development and production. Parainfluenza virus 5 (PIV5) is an appealing ve...

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Main Authors: Mooney, Alaina J., Li, Zhuo, Gabbard, Jon D., He, Biao, Tompkins, S. Mark
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536407/
https://ncbi.nlm.nih.gov/pubmed/23077318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02330-12
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