Differential Effects of Human Immunodeficiency Virus Type 1 Capsid and Cellular Factors Nucleoporin 153 and LEDGF/p75 on the Efficiency and Specificity of Viral DNA Integration

Retroviruses integrate into cellular DNA nonrandomly. Lentiviruses such as human immunodeficiency virus type 1 (HIV-1) favor the bodies of active genes and gene-enriched transcriptionally active regions of chromosomes. The interaction between lentiviral integrase and the cellular protein lens epithe...

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Bibliografiset tiedot
Päätekijät: Koh, Yasuhiro, Wu, Xiaolin, Ferris, Andrea L., Matreyek, Kenneth A., Smith, Steven J., Lee, KyeongEun, KewalRamani, Vineet N., Hughes, Stephen H., Engelman, Alan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2013
Aiheet:
Virus-Cell Interactions
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536403/
https://ncbi.nlm.nih.gov/pubmed/23097450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01148-12
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