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Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity

Lentiviruses can infect non-dividing cells, and various cellular transport proteins provide crucial functions for lentiviral nuclear entry and integration. We previously showed that the viral capsid (CA) protein mediated the dependency on cellular nucleoporin (NUP) 153 during HIV-1 infection, and no...

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Detalhes bibliográficos
Main Authors: Matreyek, Kenneth A., Yücel, Sara S., Li, Xiang, Engelman, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795039/
https://ncbi.nlm.nih.gov/pubmed/24130490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003693
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