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Lymphotoxin Alpha-Deficient Mice Clear Persistent Rotavirus Infection after Local Generation of Mucosal IgA

Rotavirus is a major cause of pediatric diarrheal illness worldwide. To explore the role of organized intestinal lymphoid tissues in infection by and immunity to rotavirus, lymphotoxin alpha-deficient (LTα(−/−)) mice that lack Peyer's patches and mesenteric lymph nodes were orally infected with...

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Bibliografski detalji
Glavni autori: Lopatin, Uri, Blutt, Sarah E., Conner, Margaret E., Kelsall, Brian L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536402/
https://ncbi.nlm.nih.gov/pubmed/23097456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01801-12
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