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Lymphotoxin Alpha-Deficient Mice Clear Persistent Rotavirus Infection after Local Generation of Mucosal IgA
Rotavirus is a major cause of pediatric diarrheal illness worldwide. To explore the role of organized intestinal lymphoid tissues in infection by and immunity to rotavirus, lymphotoxin alpha-deficient (LTα(−/−)) mice that lack Peyer's patches and mesenteric lymph nodes were orally infected with...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536402/ https://ncbi.nlm.nih.gov/pubmed/23097456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01801-12 |
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