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IgA is Important for Clearance and Critical for Protection from Rotavirus Infection

Based on a lack of severe phenotype in human IgA deficiency syndromes, the role of IgA in controlling respiratory and gastrointestinal (GI) infections has not been clearly defined. C57BL/6 and BALB/c mice lacking IgA (IgA(−/−)) were developed and used to address this question. When exposed to a comm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Blutt, Sarah E, Miller, Amber D., Salmon, Sharon L., Metzger, Dennis W., Conner, Margaret E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461240/
https://ncbi.nlm.nih.gov/pubmed/22739233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.51
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