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Tailored HIV-1 Vectors for Genetic Modification of Primary Human Dendritic Cells and Monocytes
Monocyte-derived dendritic cells (MDDCs) play a key role in the regulation of the immune system and are the target of numerous gene therapy applications. The genetic modification of MDDCs is possible with human immunodeficiency virus type 1 (HIV-1)-derived lentiviral vectors (LVs) but requires high...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536400/ https://ncbi.nlm.nih.gov/pubmed/23077304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01459-12 |
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