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The Oncogenic MicroRNA OncomiR-21 Overexpressed during Marek's Disease Lymphomagenesis Is Transactivated by the Viral Oncoprotein Meq

Gallid herpesvirus 2 (GaHV-2) is an oncogenic herpesvirus that causes T lymphoma in chicken. GaHV-2 encodes a basic leucine zipper (bZIP) protein of the AP-1 family, Meq. Upon formation of homo- or heterodimers with c-Jun, Meq may modulate the expression of viral and cellular genes involved in lymph...

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Autori principali: Stik, Grégoire, Dambrine, Ginette, Pfeffer, Sébastien, Rasschaert, Denis
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536390/
https://ncbi.nlm.nih.gov/pubmed/23055556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02449-12
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