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Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer

Developing new targeted therapy for pancreatic cancer is one of the major current challenges in cancer research. KRAS mutations and miRNA dysregulation (e.g. miR-21-5p oncomiR) play key roles in Pancreatic Ductal Adenocarcinoma (PDAC), leading to rapid progression of the disease. As the KRAS mutatio...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Gilles, Maud-Emmanuelle, Hao, Liangliang, Brown, Kaelyn, Lim, Jihoon, Bhatia, Sangeeta N., Slack, Frank J.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731108/
https://ncbi.nlm.nih.gov/pubmed/31523393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27160
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