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Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer

Developing new targeted therapy for pancreatic cancer is one of the major current challenges in cancer research. KRAS mutations and miRNA dysregulation (e.g. miR-21-5p oncomiR) play key roles in Pancreatic Ductal Adenocarcinoma (PDAC), leading to rapid progression of the disease. As the KRAS mutatio...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gilles, Maud-Emmanuelle, Hao, Liangliang, Brown, Kaelyn, Lim, Jihoon, Bhatia, Sangeeta N., Slack, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731108/
https://ncbi.nlm.nih.gov/pubmed/31523393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27160
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