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Human Anti-Varicella-Zoster Virus (VZV) Recombinant Monoclonal Antibody Produced after Zostavax Immunization Recognizes the gH/gL Complex and Neutralizes VZV Infection

Varicella-zoster virus (VZV) is a ubiquitous, highly cell-associated, and exclusively human neurotropic alphaherpesvirus. VZV infection is initiated by membrane fusion, an event dependent in part on VZV glycoproteins gH and gL. Consistent with its location on the virus envelope, the gH/gL complex is...

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書誌詳細
主要な著者: Birlea, Marius, Owens, Gregory P., Eshleman, Emily M., Ritchie, Alanna, Traktinskiy, Igor, Bos, Nathan, Seitz, Scott, Azarkh, Yevgeniy, Mahalingam, Ravi, Gilden, Don, Cohrs, Randall J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536365/
https://ncbi.nlm.nih.gov/pubmed/23077312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02561-12
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