Human Anti-Varicella-Zoster Virus (VZV) Recombinant Monoclonal Antibody Produced after Zostavax Immunization Recognizes the gH/gL Complex and Neutralizes VZV Infection

Varicella-zoster virus (VZV) is a ubiquitous, highly cell-associated, and exclusively human neurotropic alphaherpesvirus. VZV infection is initiated by membrane fusion, an event dependent in part on VZV glycoproteins gH and gL. Consistent with its location on the virus envelope, the gH/gL complex is...

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Hlavní autoři: Birlea, Marius, Owens, Gregory P., Eshleman, Emily M., Ritchie, Alanna, Traktinskiy, Igor, Bos, Nathan, Seitz, Scott, Azarkh, Yevgeniy, Mahalingam, Ravi, Gilden, Don, Cohrs, Randall J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536365/
https://ncbi.nlm.nih.gov/pubmed/23077312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02561-12
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