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Molecular Characterization of Varicella Zoster Virus in Latently Infected Human Ganglia: Physical State and Abundance of VZV DNA, Quantitation of Viral Transcripts and Detection of VZV-Specific Proteins

Varicella zoster virus (VZV) establishes latency in neurons of human peripheral ganglia where the virus genome is most likely maintained as a circular episome bound to histones. There is considerable variability among individuals in the number of latent VZV DNA copies. The VZV DNA burden does not ap...

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Détails bibliographiques
Auteurs principaux: Azarkh, Yevgeniy, Gilden, Don, Cohrs, Randall J.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016873/
https://ncbi.nlm.nih.gov/pubmed/20186615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2009_2
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