Cytotoxic Necrotizing Factor 1 and Hemolysin from Uropathogenic Escherichia coli Elicit Different Host Responses in the Murine Bladder

Cytotoxic necrotizing factor 1 (CNF1) and hemolysin (HlyA1) are toxins produced by uropathogenic Escherichia coli (UPEC). We previously showed that these toxins contribute to the inflammation and tissue damage seen in a mouse model of ascending urinary tract infection. CNF1 constitutively activates...

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Main Authors: Garcia, Tamako A., Ventura, Christy L., Smith, Mark A., Merrell, D. Scott, O'Brien, Alison D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536159/
https://ncbi.nlm.nih.gov/pubmed/23090961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00605-12
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