Cytotoxic Necrotizing Factor Type 1 Production by Uropathogenic Escherichia coli Modulates Polymorphonuclear Leukocyte Function

Many strains of uropathogenic Escherichia coli (UPEC) produce cytotoxic necrotizing factor type 1 (CNF1), a toxin that constitutively activates the Rho GTPases RhoA, Rac1, and Cdc42. We previously showed that CNF1 contributes to the virulence of UPEC in a mouse model of ascending urinary tract infec...

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Detalhes bibliográficos
Main Authors: Davis, Jon M., Rasmussen, Susan B., O'Brien, Alison D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1231104/
https://ncbi.nlm.nih.gov/pubmed/16113245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.9.5301-5310.2005
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