Epitope Mapping of Monoclonal Antibodies Capable of Neutralizing Cytotoxic Necrotizing Factor Type 1 of Uropathogenic Escherichia coli

Cytotoxic necrotizing factor type 1 (CNF1) of uropathogenic Escherichia coli belongs to a family of bacterial toxins that target the small GTP-binding Rho proteins that regulate the actin cytoskeleton. Members of this toxin family typically inactivate Rho; however, CNF1 and the highly related CNF2 a...

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Detalhes bibliográficos
Main Authors: Meysick, K. C., Mills, M., O'Brien, A. D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98131/
https://ncbi.nlm.nih.gov/pubmed/11254559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.4.2066-2074.2001
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