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Variations of Subunit ε of the Mycobacterium tuberculosis F(1)F(o) ATP Synthase and a Novel Model for Mechanism of Action of the Tuberculosis Drug TMC207
The subunit ε of bacterial F(1)F(O) ATP synthases plays an important regulatory role in coupling and catalysis via conformational transitions of its C-terminal domain. Here we present the first low-resolution solution structure of ε of Mycobacterium tuberculosis (Mtε) F(1)F(O) ATP synthase and the n...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535943/ https://ncbi.nlm.nih.gov/pubmed/23089752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01039-12 |
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