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B-cell activating factor targeted therapy and lupus

B-cell activating factor (BAFF), a member of the family of TNF-like cytokines, supports the survival and differentiation of B cells. The successful development of belimumab, a human antibody targeting soluble BAFF, has marked an important milestone in the development of biologic therapy for treatmen...

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Bibliografiske detaljer
Main Authors: Boneparth, Alexis, Davidson, Anne
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535720/
https://ncbi.nlm.nih.gov/pubmed/23281926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3920
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