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B-cell activating factor in the pathophysiology of multiple myeloma: a target for therapy?

Multiple myeloma (MM) is a currently incurable malignancy of plasma cells. Malignant myeloma cells (MMCs) are heavily dependent upon the bone marrow (BM) microenvironment for their survival. One component of this tumor microenvironment, B-Cell Activating Factor (BAFF), has been implicated as a key p...

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Detalhes bibliográficos
Publicado no:Blood Cancer J
Main Authors: Hengeveld, P J, Kersten, M J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349256/
https://ncbi.nlm.nih.gov/pubmed/25723853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2015.3
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