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Designing a functional type 2 copper center that has nitrite reductase activity within α-helical coiled coils

One of the ultimate objectives of de novo protein design is to realize systems capable of catalyzing redox reactions on substrates. This goal is challenging as redox-active proteins require design considerations for both the reduced and oxidized states of the protein. In this paper, we describe the...

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Main Authors: Tegoni, Matteo, Yu, Fangting, Bersellini, Manuela, Penner-Hahn, James E., Pecoraro, Vincent L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535669/
https://ncbi.nlm.nih.gov/pubmed/23236170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212893110
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