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Modifying the Sterics In the Second Coordination Sphere Of Designed Peptides Leads to Enhancement of Nitrite Reductase Activity
Protein design is a useful strategy to interrogate the protein structure-function relationship. We demonstrate using a highly modular 3-stranded Coiled Coil (TRI-peptide system) that a functional type 2 copper center exhibiting copper nitrite reductase (NiR) activity exhibits the highest homogeneous...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5869106/ https://ncbi.nlm.nih.gov/pubmed/29316146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201712757 |
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