DNA regions bound at low occupancy by transcription factors do not drive patterned reporter gene expression in Drosophila

In animals, each sequence-specific transcription factor typically binds to thousands of genomic regions in vivo. Our previous studies of 20 transcription factors show that most genomic regions bound at high levels in Drosophila blastoderm embryos are known or probable functional targets, but genomic...

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Bibliographische Detailangaben
Hauptverfasser: Fisher, William W., Li, Jingyi Jessica, Hammonds, Ann S., Brown, James B., Pfeiffer, Barret D., Weiszmann, Richard, MacArthur, Stewart, Thomas, Sean, Stamatoyannopoulos, John A., Eisen, Michael B., Bickel, Peter J., Biggin, Mark D., Celniker, Susan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535648/
https://ncbi.nlm.nih.gov/pubmed/23236164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209589110
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