Computational identification of developmental enhancers: conservation and function of transcription factor binding-site clusters in Drosophila melanogaster and Drosophila pseudoobscura

BACKGROUND: The identification of sequences that control transcription in metazoans is a major goal of genome analysis. In a previous study, we demonstrated that searching for clusters of predicted transcription factor binding sites could discover active regulatory sequences, and identified 37 regio...

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Detalhes bibliográficos
Main Authors: Berman, Benjamin P, Pfeiffer, Barret D, Laverty, Todd R, Salzberg, Steven L, Rubin, Gerald M, Eisen, Michael B, Celniker, Susan E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522868/
https://ncbi.nlm.nih.gov/pubmed/15345045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2004-5-9-r61
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