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IL-13-producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis
OBJECTIVE: Fibrosis is a major contributor to morbidity and mortality in systemic sclerosis (SSc). T cells are the predominant inflammatory infiltrate in affected tissues and are thought to produce cytokines that drive the synthesis of extracellular matrix proteins by fibroblasts, resulting in exces...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3535505/ https://ncbi.nlm.nih.gov/pubmed/23001877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37706 |
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