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Structural basis of aquaporin inhibition by mercury

The aquaporin family of channels was defined based on the inhibition of water transport by mercurial compounds. Despite the important role of mercurials, little is known about the structural changes involved upon mercury binding leading to channel inhibition. To elucidate the mechanism we designed a...

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Bibliografiska uppgifter
Huvudupphovsmän: Savage, David F., Stroud, Robert M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535476/
https://ncbi.nlm.nih.gov/pubmed/17376483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.02.070
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