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Structural context shapes the aquaporin selectivity filter

Aquaporins are transmembrane channels that facilitate the permeation of water and small, uncharged amphipathic molecules across cellular membranes. One distinct aquaporin subfamily contains pure water channels, whereas a second subfamily contains channels that conduct small alditols such as glycerol...

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Detalhes bibliográficos
Main Authors: Savage, David F., O’Connell, Joseph D., Miercke, Larry J. W., Finer-Moore, Janet, Stroud, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951435/
https://ncbi.nlm.nih.gov/pubmed/20855585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009864107
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