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Structural basis of aquaporin inhibition by mercury

The aquaporin family of channels was defined based on the inhibition of water transport by mercurial compounds. Despite the important role of mercurials, little is known about the structural changes involved upon mercury binding leading to channel inhibition. To elucidate the mechanism we designed a...

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Detalhes bibliográficos
Main Authors: Savage, David F., Stroud, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535476/
https://ncbi.nlm.nih.gov/pubmed/17376483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.02.070
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