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Crystal structure of human aquaporin 4 at 1.8 Å and its mechanism of conductance
Aquaporin (AQP) 4 is the predominant water channel in the mammalian brain, abundantly expressed in the blood–brain and brain–cerebrospinal fluid interfaces of glial cells. Its function in cerebral water balance has implications in neuropathological disorders, including brain edema, stroke, and head...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678640/ https://ncbi.nlm.nih.gov/pubmed/19383790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902725106 |
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