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Crystal structure of human aquaporin 4 at 1.8 Å and its mechanism of conductance

Aquaporin (AQP) 4 is the predominant water channel in the mammalian brain, abundantly expressed in the blood–brain and brain–cerebrospinal fluid interfaces of glial cells. Its function in cerebral water balance has implications in neuropathological disorders, including brain edema, stroke, and head...

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Detalhes bibliográficos
Main Authors: Ho, Joseph D., Yeh, Ronald, Sandstrom, Andrew, Chorny, Ilya, Harries, William E. C., Robbins, Rebecca A., Miercke, Larry J. W., Stroud, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678640/
https://ncbi.nlm.nih.gov/pubmed/19383790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902725106
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