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Allosteric Control of Regulated Scaffolding in Membrane Associated Guanylate Kinases

Membrane Associated Guanylate Kinases (MAGUKs) organize protein complexes at specific cellular sites by regulating interactions with their COOH-terminal Guanylate Kinase-like (GK) domains. Negative regulation of MAGUK GKs by an adjacent SH3 domain is critical for function, yet the mechanism is poorl...

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Detalles Bibliográficos
Main Authors: Marcette, Jana, Hood, Iris V., Johnston, Christopher A., Doe, Chris Q., Prehoda, Kenneth E.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535437/
https://ncbi.nlm.nih.gov/pubmed/19769408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901160f
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