Extragenic suppressor mutations that restore twitching motility to fimL mutants of Pseudomonas aeruginosa are associated with elevated intracellular cyclic AMP levels

Cyclic AMP (cAMP) is a signaling molecule that is involved in the regulation of multiple virulence systems of the opportunistic pathogen Pseudomonas aeruginosa. The intracellular concentration of cAMP in P. aeruginosa cells is tightly controlled at the levels of cAMP synthesis and degradation throug...

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Detalhes bibliográficos
Main Authors: Nolan, Laura M, Beatson, Scott A, Croft, Larry, Jones, Peter M, George, Anthony M, Mattick, John S, Turnbull, Lynne, Whitchurch, Cynthia B
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535393/
https://ncbi.nlm.nih.gov/pubmed/23233287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.49
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